O3UV  is one recommended method of administration, however, if just ozone applications is being administered, there are various ways to introduce it into the body depending on what is being treated.  Below you will find the various ways that ozone is currently administered to animals. Because of the differing size of animals these estimations of quantity may not apply.

Major Autohemotherapy (MAHT)

Major autohaemotherapy calls for the removal of between 10-250 ml of the patient’s blood. Ozone and oxygen are then injected into the blood, the ozonated blood is re-introduced into a vein. These methods have been used to treat a wide variety of health problems, including herpes, arthritis, cancer, heart disease. It is probably the most commonly used type of ozone therapy today.

Minor Autohemotherapy (mAHT) 

Minor autohaemotherapy involves removing a small amount (usually 3-10 ml) of the patient’s blood from a vein with a syringe. The blood is then treated with an equal amount of ozone and given back to the patient as an intramuscular or subcutaneous injection. The blood and ozone becomes a type of auto-vaccine, which can be very specific and effective.

Direct intra-arterial and intravenous application (DIV)

An ozone/oxygen mixture is slowly injected into an artery or vein with a hypodermic syringe. This method is used primarily for arterial circulatory disorders.  This can be used for large animals according to procedures developed by Judith Shoemaker DVM. 

Insufflation

A mixture of ozone and oxygen is introduced through the rectum and absorbed into the body through the intestine. Used for a wide variety of health problems, this method is considered one of the safest. In a typical treatment for ulcerative colitis, for example, 75 micrograms of ozone per milliliter of oxygen are used (treatment begins with 50ml of oxygen which can be increased slowly to 500 ml per treatment).

Ozonated water

This method calls for ozone gas to be bubbled through distilled water or saline.  The water is used externally to bathe wounds, burns and slow-healing skin infections. In Russia, physicians are using ozonated water to irrigate body cavities during surgery. In both Russia and Cuba, ozonated water is used to treat a wide variety of intestinal and gynecological problems, including ulcerative colitis, duodenal ulcers, gastritis, diarrhea and vulvovaginitis.  Because water doesn’t hold ozone well, it must be ozonated for about 20-30 minutes initially and then recharged every 20 minutes while it is being used.

Intra-articular injection (prolozone)

In this method, a specific mixture of procaine, vitamins, minerals and homeopathic remedies are injected directly into the joints. Ozone is also injected to the same site. It is used primarily by physicians throughout the world to treat joint pain, herniated discs, arthritis, and other joint diseases.

Intramammary infusion 

Instead of antibiotics, this can be very effective for mastitis in large animals.  The lack of side effects or residue in animals such as dairy cows makes it a perfect choice as it will not affect the quality of their milk as an antibiotic would.

Limb bagging

This non-invasive method uses a specially made plastic bag that is placed around the area to be treated. An ozone/oxygen mixture is pumped into the bag and the mixture is absorbed into the body through the skin. Ozone bagging is primarily recommended for treating leg ulcers, gangrene, fungal infections, burns and slow-healing wounds. 

Ozonated oil

Used primarily to treat skin problems, ozone gas is added to olive, hemp, sunflower or other oils and applied as a balm or salve for long term, low-dose exposure. Studies show a more rapid healing effect. 

Inhalation of ozone

Ozone can be bubbled through olive oil and the resulting atomized oil/ozone mix can be safely inhaled

Caution: The lungs are the organs most sensitive to direct ozone gas . It is not safe to breath high concentrations of ozone that have not been bubbled through an oil.

Ozone Indications and Treatment Chart

A whole number of pathological conditions exist which can be influenced positively or even healed by ozone. This is a fact which has been confirmed by a wide series of scientific investigations and medical publications. As a rule, medical ozone is applied in addition to other therapeutic methods ie it belongs to the field of complementary medicine.

As with all other forms of medical treatment, no 100 % guarantee can be given that ozone therapy will alleviate the condition it has been applied for. Success will vary according to the patient’s state of health, the frequency of ozone treatment, the doses and concentrations applied, and a number of other factors.

Oncology

MAHT can be applied with great profit in the form of an additional, biological therapy in malignant conditions. Here we make use of ozone’s immune-activating properties, produced when it is applied at a low dose. Immune cells – such as lymphocytes, helper and suppressor cells and natural killer cells – are activated via biological reactions induced by ozone to respond by producing messenger proteins called cytokines to which, for example, the interferons belong. In fact, ozone makes the body produce increased quantities of its own interferons and interleukins. On reintroduction of the ozonated blood, a cascade of positive immune reactions are set off which also contribute to general health and wellbeing.

Viral Infections

Herpes

Herpes are caused by viruses and can be treated very successfully with ozone in combination with other medical methods.
In the case of herpes, the complementary application of ozone is useful, both in the form of ozonized water and O3UV.

 Inflammatory processes of the liver

Inflammatory diseases of the liver are counted among the classical indications for medical ozone. Whereas the treatment of hepatitis A (HVA = hepatitis virus A) is relatively unproblematic and produces complete healing, another form, hepatitis B (HVB = hepatitis virus B), frequently takes a chronic course. Here, in addition to classical medical treatment methods, we find that ozone autohaemotransfusion or the rectal insufflation of controlled ozone/oxygen gas quantities can be successful. This also applies to the treatment of hepatitis C which, due to an incubation period capable of lasting for a number of years, is generally not diagnosed as a liver disease until it has become a chronic condition.

 

Bacterial/Fungal Infections

Fungal skin infections and infected skin lesions

The fungicidal and bactericidal properties of ozone have been successfully in use for over 100 years in the treatment of water for drinking. They make medical ozone an effective therapeutic agent in combating persistent skin moulds and fungi, especially those of the paws with bacterial infections, fungal infections of the trunk or against fungal/mycotic infections of the mucous membranes.

Infected wounds

The local treatment of infected wounds, such as may easily occur with open bed sores (decubitus), ulcers of the lower leg (ulcus cruris), diabetic gangrene or delayed/disturbed wound healing processes, belong to the classical application fields of medical ozone. Here we+ primarily make use of its disinfectant, ie bactericidal and fungicidal, effects, to obtain a germ-free and clean wound. Once this has been achieved, we then apply lower doses of O3 gas to accelerate/improve wound healing. 

Inflammatory Conditions

Chronic polyarthritis

The term arthritic/rheumatic conditions includes various painful diseases of the skeletal or muscular system, partly also involving functional restrictions. In general, the application of medical ozone can here be regarded as being a complementary measure only, combined with a basic classical method and corresponding physiotherapy. In the case of rheumatic arthritis (chronic polyarthritis), our experience shows that ozone autohaemotherapy is a very useful complementary form when given during the non-acute phases. Its immunomodulatory and antiinflammatory properties are here its basic principle of action.

When we divide inflammatory diseases of the joints into three phases, it is particularly stages 1 and 2, ie those not yet involving a severe bone deformation, that are responsive to medical ozone application. This applies to gonarthritis (inflammation of the knee joint) or the active arthritic form in knee and shoulder joints. Here, intraarticular ozone injections applied in addition to basic standard medical methods – in this case specific exercise therapy measures – are of great use. We here make full use of the antiinflammatory effects of ozone, in addition to its immunomodulatory properties and its ability to activate cartilage metabolism. 

Circulatory Conditions

Arterial circulatory disorders, for which, among other symptoms, a feeling of coldness in the legs or pains after walking only short distances (“short cut” syndrome) are alarming signs, have been a classical indication for ozone therapy for over 40 years now. Its success has been confirmed by a large number of clinical trials. Ozone is applied as a complement to and in combination with other methods in classical and complementary medicine.

Autoimmune Disorders

 

Respiratory Disorders

 

Other Conditions

Regeneration and revitalization

Animals that are exhibiting excessive mental and physical tension respond particularly well to O3 application. Its ability to activate red and white blood cell metabolism produces an improvement in general wellbeing, and brings about a general revitalization.

Older animals – Prevention and therapy

Animals that are advanced in years respond very well to medical ozone therapy.  There are multiple advantages  such as that of making an improved supply of oxygen accessible to all tissues, mobilizing the immune system, and activating the body’s own supply of antioxidants and radical scavengers.  Furthermore, we have its positive influence in cerebral circulatory disorders – a condition characterized by a general reduction in physical performance, insecurity in walking, dizziness.  In addition to other measures applied in complementary medicine, medical ozone is also used as a preventive, contributing to a marked increase in life quality.

Diseases of the eye

Circulatory disturbances due to old age also affect the eye with atrophic and degenerative changes. For example, senile macular degeneration is well known, occurring at the center of the retina – the point where visual focus is at its sharpest. Its sequels are thus able to influence the optic nerve to varying degrees, producing what is called optic nerve atrophy. Results obtained from a clinical trial carried out at the University of Siena show, in addition to reports from practical applications, improvements in vision lasting for 6 to 8 months after an MAHT (Major Auto Hemo Therapy).  Continuing the series of treatments can produce further improvement in visual performance or prevent it from worsening. 

Intestinal diseases – prostatic and colitis

In the case of inflammatory intestinal processes, particularly during their early stages, the local application of ozone in the form of rectal O3 gas insufflation has been proved very useful. A series of 10 ozone applications is sufficient in most cases. Several such series are only necessary in about 10 % of the patients (from a prostatic clinical study on O3 involving 248 patients).

Contraindication

Contraindications for ozone therapy are the following:
– acute and chronic tendency to bleedings;
– thrombocytopenia;
– hyperthyroidism;
– cramps in the anamnesis;
– individual intolerance to ozone;
– blood coagulation disorder;
Ozone should be used most carefully in case of decompensated conditions:
– in decompensated heart insufficiency;
– in severe acute toxication (incl. alcohol);
– in hypoglycemic conditions;
– in extremal sympathicotonic and parasympathicotonic reactions.
After myocardial infarction ozone therapy can be used not earlier than after 6 months, in patients with hemorrhagic insult in the anamnesis ozone therapy is not recommended for use.

Intra-articular injection (prolozone)

In this method, a specific mixture of procaine, vitamins, minerals and homeopathic remedies are injected directly into the joints. Ozone is also injected to the same site. It is used primarily by physicians throughout the world to treat joint pain, herniated discs, arthritis, and other joint diseases.

 

Intramammary infusion 

Instead of antibiotics, this can be very effective for mastitis in large animals.  The lack of side effects or residue in animals such as dairy cows makes it a perfect choice as it will not affect the quality of their milk as an antibiotic would.

 

Limb bagging

This non-invasive method uses a specially made plastic bag that is placed around the area to be treated. An ozone/oxygen mixture is pumped into the bag and the mixture is absorbed into the body through the skin. Ozone bagging is primarily recommended for treating leg ulcers, gangrene, fungal infections, burns and slow-healing wounds.