A Brief History of Ozone

A Brief History of Ozone

Discovery History of ozone

Although ozone was discovered in 1785 by Dutch physicist Martinus Van Marum (1750-1837) as he perceived a peculiar odor that was generated near electrostatic machines, it was not until May 1840 that the German chemist Christian Friedrich Schönbein (1799-1868) synthesized it.


Christian Friedrich Schönbein

In 1857 Werner von Siemens built the first superior induction tube with which Kleinmann made the first attempt to destroy microorganisms and also performed the first gas insufflations in animals and humans. In 1870, the German doctor Lender published the first paper ever on practical biological effects relating to water disinfection. The discovery of the antimicrobial properties of ozone revolutionized medicine during this time as it would still be seventy years before the emergence of penicillin.
In 1873 Fox discovered the ability of this chemical agent for eliminating microorganisms. According to Dr. Kellogg in his book on diphtheria, there is evidence to its use as a disinfectant since 1881. This discovery crossed the ocean to North America and in 1885, the Florida Medical Association published the first textbook on medical applications of ozone.
In 1893, the first facility in Ousbaden (Netherlands) for the disinfection and purification of water for human consumption and waste was created. To date, there are more than 3,000 water treatment plants with ozone in the Netherlands alone. Zurich, Florence and other cities have been acquiring these systems to disinfect water.



Nikola Tesla (1856-1943) of Croatian origin and later on a US citizen, patented his first ozone generator in 1896 and in 1900 founded “Tesla Ozone Co., manufacturer of generators for medical use. Tesla was also the first to ozonate olive oil.

In 1898 Drs. Thauerkauf and Luth created the Institute of Oxygen-Ozone Therapy in Germany and publish the first studies in animals.

Medical Ozone in the XX Century

United States

The first American therapeutic use of ozone was by Dr. John H. Kellogg in ozone steam saunas at his Battle Creek, Michigan sanitarium in 1880 as he wrote in his book, Diptheria: Its Nature, Causes, Prevention and Treatment.

John Kellogg

In 1902, Dr. Charles Linder of Spokane, Washington was written up in an article in a local paper which stated that he had injected ozone as a part of his standard medical practice.

In 1904, “The Medical Uses of Hydrozone (ozonated water) and Glyzozone (ozonated olive oil) by Charles Marchand, a New York chemist, appeared in its 19th edition. Believe it or not, this book is in the Library of Congress with the US Sergeon General’s stamp of approval on it.

In 1911, A Working Manual of High Frequency Currents was published by Dr. Noble Eberhart, the head of the Dept. of Physiologic Therapeutics at Loyola University, Chicago. In Chapter 9, he details the use of zone to treat tuberculosis, anemia, chlorosis, tinnitus, wooping cough, asthma, bronchitis, hay fever, insomnia, pneumonia, diabetes, gout and syphilis.

In 1912, Dr. H.C. Bennett published Electro-Therapeutic Guide. In that publication, he described the use of Ozol (ozone breathed after running it through eucalyptus, pine or thyme oils).

In 1929, a book called Ozone and its Therapeutic Action was published in the US listing 114 diseases and how to treat them with ozone. Its 40 authors were leaders in many of the prominent hospitals of the time.

Finally, in 1933, the decline of a promising treatment began as the discovery of penicillin and insulin rocketed the drug market forward. Ozone and other treatments slowly lost favor as pharmaceutical giants heavy influence on the medical culture began a shift in power that still exists.

Today, there are hundreds of medical doctors and veterinarians here in the US who use ozone to treat their patients every day.

In 1913, Dr. Blass founded the first German association of ozone therapy. Meanwhile, the First World War in Europe had just exploded. In 1915, Dr. Wolf, chief surgeon of the medical services of the German army, extends its use for topical treatment of infected wounds, frozen foot, gangrene and decubitus ulcers.
in 1932, a Swiss dentist, Dr. Fish, published a paper on the applications of ozone in dentistry to treat caries, and also patented the first device specifically for this application, the Cytozon.
In 1935 Edwin Payr (Austrian-German) showed the wound healing effect of ozone. In Germany, after the outbreak of World War II, Dr. Wolf published “Medical Ozone”, which is considered THE classic book on ozone therapy.
Despite its obvious usefulness, ozone as a healing method for infectious diseases gradually fell into disuse. Moreover, in 1940, the U. S. Food and Drug Administration (FDA) sealed the fate of medical ozone generators by promoting their own pharmaceutical industry which was reinforced after the acquisition of a pharmaceutical giant, German Bayer.
The emergence of ozone resistant plastics lead German physician Dr. Hänsler to manufacture the first modern ozone generator in 1957.
In 1961 Dr. Hans Wolff introduced major and minor autohemotherapy into his practice and in the early 70’s the German Society of Ozone Therapy was created which contributed to the momentum of ozone therapy and its application in various diseases.

In the 70’s the first communications from the Russians on the successful use of ozone in burned patients appeared. At the same time, in Minsk (Belarus), the first patients were successfully treated for bronchial asthma with ozonated steam inhalations.
The most enthusiastic students and researchers of ozone in this part of the world, have been scientists, members of the Central Laboratory of Scientific Research of the State Academy of Medicine of Nizhny Novgorod (former Gorki), under the direction of the academician Ramn B. A. Koroleva. There, on October 1977, the first experiment on dogs with ozonated saline solution was performed.
As the Russians studied the potential of ozonated saline, they also began to develop new methods for the application of ozone such as the use of ozone in the preservation
of blood, blood ozonation and the infusion of ozonated saline during periods of post-operative and post-resuscitation. (Ozone Therapy Manual, Nizhny Novgorod, 2008. Translation from Russian into Spanish Adriana Schwartz).
In 2005, the Russians were the first to record the use of ozone in dermatology and cosmetology at state level. Two year later, in 2007, they also reported its use in gynecology-obstetrics, neonatology, traumatology and burn treatment. Russia became the first country in the world to regularize and implement ozone therapy at the state level.

Cuba-Ozone-CenterIn 1982, ozone was already used in Cuba in water disinfection and other environments. At that time it started doing research on medical applications of ozone in the National Center for Scientific Research (CNIC), the most experienced scientific institution in the country.
In 1988, the First National Congress on Ozone Applications was held, involving many and in 1990, the 1st Ibero Latin American Congress of Ozone Therapy took place.
In 1992 the Ozone Research Center was created by the CNIC Department of Ozone.
Since 2009 ozone therapy has been applied throughout all of Cuba according to the Ministerial Resolution 261 issued by the Ministry of Public Health.

Ozone Therapy Throughout the World
At present there are more than 40 national and international associations
that bring together the professionals that practice this therapy as well as indexed specialized journals, continuing training courses and ozone conferences. In the US it is the American Academy Ozone Therapy (AAOT). There are also over 26,000 ozone therapists throughout the world.

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